Join us   Log in  

THE JOURNAL OF SCHOOL AND UNIVERSITY MEDICINE - Volume 7 Issue 1-2, January - June 2020

Pages: 29-36
Print Article   Download XML  Download PDF


Author: Dr. Mihai Mara

Category: Medical


The appearance of the new coronavirus in January 2020 and its rapid spread took the medical world by surprise. The high degree of contagiousness, the severity of the symptoms and the lack of a specific treatment mobilized the medical staff in an unprecedented and superhuman collective effort. More than three months after the pandemic started, new things about COVID-19 disease are still being studied and discovered, and the most appropriate therapeutic protocols are still being sought. This article is intended to be a synthesis of the latest studies on the new coronavirus for a better understanding of the invisible enemy we are fighting during this period.

Keywords: coronavirus, SARS-CoV-2, COVID-19


1. Wikipedia Coronavirus: accesat 10.05.2020

2. Licker M, Brehar Cioflec D. Curs de microbiologie special?, Vol. II Virusologie, Micologie, 2020 - Universitatea de Medicin? ?i Farmacie Victor Babes Timi?oara - pag 61, link accesat 11.05.2020

3. Cherry J, Demmler-Harrison GJ, Sheldon LK, Steinbach WJ, Hotez PeJ. Feigin and Cherry's Textbook of Pediatric Infectious Diseases. Elsevier Health Sciences. 2017 PT6615. ISBN 978-0-323-39281-5.

4. Woo PC, Huang Y, Lau SK, Yuen KY. "Coronavirus genomics and bioinformatics analysis". Viruses. 2010;2(8):1804–20. doi:10.3390/v2081803. PMC 3185738. PMID 21994708. Link accesat 11.05.2020:

5. Wertheim JO, Chu DK, Peiris JS, Kosakovsky Pond SL, Poon LL. "A case for the ancient origin of coronaviruses". Journal of Virology. 2013;87(12):7039–45. doi:10.1128/JVI.03273-12. PMC 3676139. PMID 23596293.

6. WorldoMeter Coronavirus cases: accesat 13.05.2020

7. "Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003". World Health Organization. April 2004.

8. Gorbalenya AE, Baker SC, Baric RS, de Groot RJ, Drosten C, Gulyaeva AA, et al. "The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2". Nature Microbiology 2020;5(4):536–544. doi:10.1038/s41564-020-0695-z. PMC 7095448. PMID 32123347. Accesat 12.05.2020

9. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19) (PDF) (Report). World Health Organization (WHO). 24 February 2020. Accesat 11.05.2020

10. Xiao K, Zhai J, Feng Y. "Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolin" 2020 Link accesat în data de 10.05.2020

11. Wikipedia SARS-CoV2 Accesat 12.05.2020

12. Xu X, Chen P, Wang J, Feng J, Zhou H, Li X, et al. "Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission". Science China Life Sciences 2020;63(3):457–460. doi:10.1007/s11427-020-1637-5. PMC 7089049. PMID 32009228. Accesat 13.05.2020

13. Wang K, Chen W, Zhou YS, Lian JQ, Zhang Z, Du P, et al. SARS-CoV-2 invades host cells via a novel route: CD147-spike protein 2020 (PDF). Accesat 13.05.2020

14. "Interim Clinical Guidance for Management of Patients with Confirmed Coronavirus Disease (COVID-19)" CDC, , accesat 15.05.2020

15. Hamming I, Timens W, Bulthuis ML, Lely AT, Navis G, van Goor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol. 2004;203(2):631?637 accesat 16.05.2020

16. Wikipedia COVID-19 Accesat 12.05.2020

17. Sperati J. Coronavirus: Kidney Damage Cuased by COVID-19. Link accesat 17.05.2020

18. Bourouiba Lydia "Turbulent Gas Clouds and Respiratory Pathogen Emissions - Potential Implications for Reducing Transmission of COVID-19”, JAMA Network 2020;323(18):1837-1838. doi:10.1001/jama.2020.4756 26.03.2020,, accesat 12.05.2020

19. Fiorillo L, Cervino G, Matarese M et all. COVID-19 Surface Persistence: A Recent Data Summary and Its Importance for Medical and Dental Settings. Int. J. Environ. Res. Public Health 2020;17(9):3132; accesat 12.05.2020

20. "Rata de reproducere a coronavirusului cre?te din nou în Germania: fiecare 10 oameni bolnavi infecteaz? al?i 9" - ziar online, 24.04.2020 accesat 15.05.2020

21. " Rata infect?rilor în Germania a crescut, la câteva zile de la relaxarea restric?iilor" - ziar online 10 mai 2020, accesat 15.05.2020

22. Sanche S, Lin YT, Xu C et all. 2020. " High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2" accesat 16.05.2020

23. Basic reproduction number accesat 15.05.2020

24. Informatii pentru personalul medico-sanitar, site INSP accesat 17.05.2020

25. Kampf G, Todt D, Pfaender S, Steinmann E. Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents. J Hosp Infect. 2020;104(3):246?251. doi:10.1016/j.jhin.2020.01.022 Link accesat 17.05.2020

26. WHO/Europe publishes considerations for gradual easing of COVID-19 measures. 24 aprilie 2020. accesat 05.05.2020