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      <JournalTitle>The Journal of School and University Medicine</JournalTitle>
      <Volume-Issue>Volume 6 Issue 2</Volume-Issue>
      <Season>April - June 2019</Season>
      <Abstract>The Von Hippel-Lindau syndrome belongs to  a rare diseases category and it is autosomal dominant  inherited. It is caused by an alteration of the VHL  gene on the short arm of chromosome 3. The inci &#13;
dence of this syndrome is 1/36000 newborns. The  Von Hippel-Lindau syndrome is characterized by benign or malign tumors at the level of several organs,  tissues and systems in patients with a suggestive family medical history. &#13;
The presence of a retinal or cerebral hemangioblastoma can suggest a Van Hippel-Lindau syndrome  &#13;
and imposes supplementary investigation for detecting the presence of tumors also in other organs. This  syndrome can be detected from early childhood to  young adult age. &#13;
Secondary prevention significantly increases  the life expectancy for this category of patients. The  present article presents the case study of a female student, 20 years old, with a positive family background  for the Von Hippel-Lindau syndrome (father and  brother both with a positive diagnosis), which manifested the first symptoms of the syndrome when she  was 18 years old.</Abstract>
      <Keywords>boala Hippel-Lindau, studenta</Keywords>
        <Abstract>https://revista-medicina-scolara.ro/ubijournal-v1copy/journals/abstract.php?article_id=9263&amp;title=A RARE CASE OF VON HIPPEL-LINDAU DISEASE  IN A STUDENT</Abstract>
        <References>1. https://www.ncbi.nlm.nih.gov/genome/tools/gdp 2. Lenders JW, Duh QY, Eisenhofer G, Gimenez-Roque plo AP, Grebe SK, Murad MH, et al. Pheochromocytoma and  paraganglioma: an endocrine society clinical practice guide line.J Clin Endocrinol Metab. 2014 Jun. 99(6):1915-42.  3. Arun C Guliani, MD; Mampton Roy, Sr MD.Von Hip pel-Lindau Disease may 7, 2017.https://emedicine.medscape. com/article/1219430-overview &#13;
4. Catapano D, Muscarella LA, Guarnieri V, Zelante L,  D’Angelo VA, D’Agruma L. Hemangioblastomas of central  nervous system: molecular genetic analysis and clinical man agement.Neurosurgery.2005;56:1215–21. &#13;
5. Giannini C, Scheithauer BW, Hellbusch LC, Rasmus sen AG, Fox MW, McCormick SR, Davis DH. Peripheral  nerve hemangioblastoma.Mod Pathol.1998;11:999–1004. &#13;
6. Huson SM, Harper PS, Hourihan MD, Cole G, Weeks  RD, Compston DA. Cerebellar haemangioblastoma and von  Hippel-Lindau disease.Brain. 1986 Dec. 109 (Pt 6):1297-310.  &#13;
7. Hamish Smith, Yuranga Weerakkody et al. Von Hip pel-Lindau Diseases. https://radiopaedia.org/articles/von-hip pel-lindau-disease-5  &#13;
8. Ganeshan D, Menias CO, Pickhardt PJ, Sandrasega ran K, Lubner MG, Ramalingam P, Bhalla S. Tumors in von  Hippel-Lindau Syndrome: From Head to Toe-Comprehensive  State-of-the-Art Review. (2018) Radiographics : a review  publication of the Radiological Society of North America,  Inc. 38 (3): 849-866.doi:10.1148/rg.2018170156  &#13;
9. h t t p s : / / e m e d i c i n e . m e d s c a p e . c o m / a r t i - cle/1219430-overview &#13;
10. http://www.endocrinopedia.info/2015/07/sindromul von-hippel-lindau.html</References>