THE JOURNAL OF SCHOOL AND UNIVERSITY MEDICINE - Volume 8 Issue 1, January-March 2021
Pages: 36-40
Date of Publication: 15-Apr-2021
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MULTISYSTEM INFLAMMATORY SYNDROME ASSOCIATED SARS-COV-2. A NOVEL SPECTRUM OF PEDIATRIC ILNESS
Author: Simona Cainap, Alexandra Mititelu, Oana Pantar, Diana Lazar
Category: Medical
Abstract:
Multisystem Inflammatory Syndrome associated with COVID-19 (MIS-C) has been described as a novel and often severe presentation of SARS-CoV-2 infection in children.
This syndrome is characterized by fever, abdominal pain, gastrointestinal and cutaneous symptoms, and hemodynamic alterations. MIS-C has similar features to those of Kawasaki disease (KD), toxic shock syndrome (TSS), macrophage-activation syndrome, bacterial sepsis, meningitis.
MIS-C is defined as a typically progressive disease. Patients who initially had mild symptoms can develop severe illness with multi-organ dysfunction a few days after symptom onset.
The majority of affected children were treated with intravenous immune globulin (IVIG), and several also received adjunctive high-dose steroids.
The pediatricians should be aware about this new and potentially life threatening condition in children during COVID-19 epidemics.
Keywords: Covid-19, Multisystemic inflammatory syndrome, children
DOI: 10.51546/JSUM.2021.8106
DOI URL: http://dx.doi.org/10.51546/JSUM.2021.8106
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